TFAA/H3PO4 mediated unprecedented N-acylation of carbazoles leading to small molecules possessing anti-proliferative activities against cancer cells.

نویسندگان

  • Sunder Kumar Kolli
  • Bagineni Prasad
  • P Vijaya Babu
  • Mohd Ashraf Ashfaq
  • Nasreen Z Ehtesham
  • R Ramesh Raju
  • Manojit Pal
چکیده

For the first time TFAA/H3PO4 has facilitated the direct and metal-free N-acylation of carbazoles leading to a number of N-acylated derivatives. Several of these compounds were found to be promising when tested for their anti-proliferative properties against oral cancer cell lines.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 12 32  شماره 

صفحات  -

تاریخ انتشار 2014